Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991983 | 0.92 | STS (0.53) | ESR1STSMAPTNPC1RAB9A | |
| SCHEMBL17988668 | 0.92 | STS (0.53) | ESR1STSMAPTNPC1RAB9A | |
| SCHEMBL17988672 | 0.87 | ESR1 (0.47) | ESR1STSMAPTNPC1RAB9A | |
| SCHEMBL17988686 | 0.77 | MAPT (0.50) | STSMAPTNPC1RAB9AMEN1 | |
| SCHEMBL14699614 | 0.77 | MAPT (0.50) | STSMAPTNPC1RAB9AMEN1 | |
| SCHEMBL17988671 | 0.77 | PTGS2 (0.47) | ESR1STSMAPTNPC1RAB9A | |
| SCHEMBL17992018 | 0.77 | ESR1 (0.41) | ESR1STSMAPTPTGS2MEN1 | |
| SCHEMBL17991992 | 0.73 | LMNA (0.49) | MAPTNPC1RAB9APTGS2MEN1 | |
| SCHEMBL17988683 | 0.73 | STS (0.66) | STSMAPTNPC1RAB9A | |
| SCHEMBL17991985 | 0.72 | LMNA (0.45) | STSMAPTNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |