Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | ESRRG | P62508 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17988668 | 1.00 | STS (0.53) | STSPTGS2ESR1ESR2MAPT | |
| SCHEMBL17991977 | 0.92 | ESR1 (0.47) | STSPTGS2ESR1ESR2MAPT | |
| SCHEMBL17988672 | 0.91 | ESR1 (0.47) | STSPTGS2ESR1ESR2MAPT | |
| SCHEMBL17988671 | 0.85 | PTGS2 (0.47) | STSPTGS2ESR1ESR2MAPT | |
| SCHEMBL17988670 | 0.80 | CYP19A1 (0.63) | STSPTGS2ESR1ESR2CYP3A4 | |
| SCHEMBL17988693 | 0.79 | PTGS2 (0.44) | PTGS2MAPTNPC1CYP2D6RAB9A | |
| SCHEMBL17988686 | 0.78 | MAPT (0.50) | STSMAPTMEN1KMT2ANPC1 | |
| SCHEMBL14699614 | 0.78 | MAPT (0.50) | STSMAPTMEN1KMT2ANPC1 | |
| SCHEMBL17991992 | 0.76 | LMNA (0.49) | PTGS2MAPTMEN1KMT2ANPC1 | |
| SCHEMBL17992018 | 0.76 | ESR1 (0.41) | STSPTGS2ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409859-B2 | Substituted diphenyl derivatives | CREATIVE THERAPEUTICS GMBH (DE) | 2016-08-09 | — | — | US | disclosed |