Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653021 | 1.00 | KMT2A (0.43) | KMT2AITGB1ITGA4ALDH1A1MEN1 | |
| SCHEMBL7276715 | 0.81 | CRHBP (0.44) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL7276719 | 0.81 | CRHBP (0.44) | KMT2AALDH1A1MEN1MAPTPOLB | |
| Water SCHEMBL10716192 | 0.80 | CRHBP (0.43) | KMT2AALDH1A1MEN1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL6371205 | 0.80 | CRHBP (0.43) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL10603362 | 0.78 | GPR35 (0.44) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL1653003 | 0.78 | GPR35 (0.44) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL31711243 | 0.77 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1POLBL3MBTL1 | |
| SCHEMBL1695820 | 0.77 | GPR35 (0.43) | KMT2AALDH1A1MEN1MAPTPOLB | |
| SCHEMBL8749879 | 0.77 | HCAR3 (0.43) | KMT2AALDH1A1MEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229973-B2 | pH-sensitive polymeric micelles for drug delivery | UTAH, UNIVERSITY OF RESEARCH FOUNDATION | 2007-06-12 | — | — | US | claimed |
| US-20050070721-A1 | PH-sensitive polymeric micelles for drug delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2005-03-31 | — | — | US | claimed |
| US-8263664-B2 | pH-sensitive polymeric micelles for drug delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-09-11 | — | — | US | disclosed |
| US-7951846-B2 | pH-sensitive polymeric micelles for drug delivery | BAE YOU HAN | 2011-05-31 | — | — | US | disclosed |
| US-7659314-B2 | PH-sensitive polymeric micelles for drug delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-02-09 | — | — | US | disclosed |
| US-20100009926-A1 | PH-SENSITIVE POLYMERIC MICELLES FOR DRUG DELIVERY | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090274753-A1 | PH-SENSITIVE POLYMERIC MICELLES FOR DRUG DELIVERY | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2009-11-05 | — | — | US | disclosed |
| US-7229973-B2 | pH-sensitive polymeric micelles for drug delivery | UTAH, UNIVERSITY OF RESEARCH FOUNDATION | 2007-06-12 | — | — | US | disclosed |
| US-20050186263-A1 | PH-sensitive polymeric micelles for drug delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2005-08-25 | — | — | US | disclosed |
| US-20050070721-A1 | PH-sensitive polymeric micelles for drug delivery | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2005-03-31 | — | — | US | disclosed |