Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380493 | 0.92 | HSPA1A (0.35) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL18475716 | 0.86 | KMT2A (0.44) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL29395615 | 0.77 | SCN2A (0.57) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL885606 | 0.77 | SCN2A (0.57) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL17993531 | 0.77 | LMNA (0.50) | SCN2AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL18470136 | 0.71 | KMT2A (0.47) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL17993493 | 0.70 | SCN2A (0.50) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL17993459 | 0.70 | SCN2A (0.43) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL21942500 | 0.69 | GAA (0.48) | HSPA1APABPC1SCN2AKMT2AMEN1 | |
| SCHEMBL28247030 | 0.69 | TLR9 (0.64) | ALDH1A1NPSR1HTTTDP1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054498-A1 | Bisimidazodiazocines | Idemitsu Kosan Co., Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |