Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | UTRN | P46939 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL14158710 | 0.93 | TBK1 (0.40) | PTGS2HDAC6ATRTBK1PTPN2 | |
| SCHEMBL17965092 | 0.79 | HDAC6 (0.41) | PTGS2HDAC6HDAC3HDAC8QDPR | |
| SCHEMBL14157442 | 0.77 | PTGS2 (0.36) | PTGS2HDAC6PTPN2PTPN1PTPN5 | |
| SCHEMBL14695343 | 0.76 | MMP2 (0.44) | PTGS2HDAC6 | |
| SCHEMBL14707117 | 0.76 | USP7 (0.39) | PTGS2HDAC6TBK1UTRNHDAC3 | |
| SCHEMBL14158855 | 0.76 | GPR119 (0.50) | ATRTLR7 | |
| SCHEMBL14695589 | 0.75 | PTGS2 (0.45) | PTGS2HDAC6PTPN2PTPN1PTPN5 | |
| SCHEMBL14695345 | 0.74 | MMP2 (0.44) | HDAC6UTRNHDAC3HDAC8TLR9 | |
| SCHEMBL27007924 | 0.73 | HTR2C (0.50) | TBK1QDPR | |
| SCHEMBL4261152 | 0.71 | HTR2C (0.56) | PTGS2QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | disclosed |