Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 13/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20313757 | 0.88 | F11 (0.59) | F11KLKB1 | |
| SCHEMBL1197747 | 0.83 | KMT2A (0.47) | F11KLKB1 | |
| SCHEMBL1197749 | 0.83 | KMT2A (0.47) | F11KLKB1 | |
| SCHEMBL10258220 | 0.78 | KMT2A (0.52) | F11 | |
| SCHEMBL8094866 | 0.77 | F11 (0.65) | F11KLKB1 | |
| SCHEMBL12352534 | 0.76 | KMT2A (0.52) | F11 | |
| SCHEMBL13073915 | 0.76 | F11 (0.61) | F11KLKB1 | |
| SCHEMBL13267005 | 0.76 | F11 (0.73) | F11KLKB1 | |
| SCHEMBL3004580 | 0.76 | F11 (0.73) | F11KLKB1 | |
| SCHEMBL3667315 | 0.76 | F11 (0.54) | F11KLKB1F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229839-A1 | Factor XIa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-08-11 | — | — | US | disclosed |
| US-20150183770-A1 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBVIE DEUTSCHLAND (DE) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183770-A1 | 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | HTR5A, HTR3A, HTR6 | F11 4448/4885KLKB1 4570/4885F9 4846/4885 |
| US-20160229839-A1 | Factor XIa Inhibitors | F11, SERPINC1, TFPI | F11 1/4885KLKB1 14/4885F9 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.