Sugi Predict

Sugi Predict / Compounds / SCHEMBL1799649

SCHEMBL1799649

SCHEMBL1799649

CC(C)(C)OC(=O)NS(N)(=O)=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 13/20 0.50
▸ CA2 P00918 12/20 0.50
▸ CA12 O43570 11/20 0.50
▸ CA14 Q9ULX7 5/20 0.50
▸ CA7 P43166 4/20 0.50
▸ CA9 Q16790 8/20 0.43
▸ FNTA P49354 1/20 0.42
▸ FNTB P49356 1/20 0.42
▸ PGGT1B P53609 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.37
▸ DGAT1 O75907 1/20 0.37
▸ CA4 P22748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18122530 0.81 CA12 (0.41) CA1CA2CA12CA14CA7
SCHEMBL3762126 0.79 CA12 (0.52) CA1CA2CA12CA14CA7
SCHEMBL13217304 0.79 CA12 (0.52) CA1CA2CA12CA14CA7
SCHEMBL756075 0.79 CA12 (0.52) CA1CA2CA12CA14CA7
SCHEMBL192415 0.79 CA12 (0.52) CA1CA2CA12CA14CA7
SCHEMBL25472477 0.77 CA12 (0.50) CA1CA2CA12CA14CA7
SCHEMBL29098389 0.77 CA12 (0.50) CA1CA2CA12CA14CA7
SCHEMBL29084558 0.77 CA12 (0.50) CA1CA2CA12CA14CA7
SCHEMBL2011562 0.77 CA12 (0.50) CA1CA2CA12CA14CA7
SCHEMBL14253505 0.76 CA12 (0.58) CA1CA2CA12CA14CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130131018-A1 SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS EXONHIT S.A. (FR) 2013-05-23 — — US claimed
EP-2576514-A1 SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS EXONHIT SA (FR) 2013-04-10 — — EP claimed
WO-2011151423-A1 SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS EXONHIT S.A. (FR) 2011-12-08 — — WO claimed
CN-102174047-A Novel process for preparing doripenem HUNAN OUYA BIOLOG CO LTD 2011-09-07 — — CN claimed
WO-2011073273-A1 BENZOXAZINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS EVOTEC AG (DE) 2011-06-23 — — WO claimed
WO-2011073277-A1 PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS EVOTEC AG (DE) 2011-06-23 — — WO claimed
EP-4514784-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-03-05 — — EP disclosed
US-20240043410-A1 SULPHAMOYL UREA DERIVATIVES CONTAINING ALKYL-OXACYCLOALKYL MOIETY AND USES THEREOF NodThera Limited (GB) 2024-02-08 — — US disclosed
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE LOXO ONCOLOGY, INC. 2024-01-18 — — US disclosed
WO-2023212693-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PETRA PHARMA CORPORATION (US) 2023-11-02 — — WO disclosed
CN-116848091-A Inhibitors of ectonucleotide pyrophosphatase-phosphodiesterase-1 (ENPP 1) and uses thereof 1CBIO公司 2023-10-03 — — CN disclosed
CN-116783184-A Sulfamoylurea derivatives containing alkyl-oxacycloalkyl moieties and uses thereof 诺瑟拉有限公司 2023-09-19 — — CN disclosed
EP-4208459-A1 SULPHAMOYL UREA DERIVATIVES CONTAINING ALKYL-OXACYCLOALKYL MOIETY AND USES THEREOF Nodthera Limited (GB) 2023-07-12 — — EP disclosed
WO-1997029092-A1 HISTAMINE H3 RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 1997-08-14 — — WO disclosed
CN-1034571-C A method for producing a pyrrolidire derivative SHIONOGI & CO (JP) 1997-04-16 — — CN disclosed
CN-1032257-C Process for producing pyrrolidinethinyl carbapenem derivatives SHIONOGI SEIYAKU KK (JP) 1996-07-10 — — CN disclosed
CN-1113233-A A method for producing a pyrrolidire derivative SHIONOGI & CO (JP) 1995-12-13 — — CN disclosed
US-5317016-A Pyrrolidylthiocarbapenem derivative SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-31 — — US disclosed
CN-1071428-A Pyrrolidinylthiocarbapenem derivatives SHIONOGI & CO (JP) 1993-04-28 — — CN disclosed
EP-0528678-A1 A pyrrolidylthiocarbapenem derivative SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1993-02-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018115-A1 ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE PIK3CA, PIK3R4, PIK3R5 CA1 4669/4885CA2 3132/4885CA12 4588/4885
US-20130131018-A1 SUBSTITUTED ISOQUINOLINES AND THEIR USE AS TUBULIN POLYMERIZATION INHIBITORS TUBB3, TUBB, TUBB1 CA1 4164/4885CA2 3512/4885CA12 4658/4885
US-20240043410-A1 SULPHAMOYL UREA DERIVATIVES CONTAINING ALKYL-OXACYCLOALKYL MOIETY AND USES THEREOF NOD1, IL1B, NLRP3 CA1 3076/4885CA2 3847/4885CA12 4465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.