Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27564569 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| Acetic Acid SCHEMBL3434835 | 0.91 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| Formamide SCHEMBL27740418 | 0.91 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| SCHEMBL304332 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL211474 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| Hydrochloric Acid SCHEMBL6239673 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| SCHEMBL21013404 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| SCHEMBL4602665 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| SCHEMBL27564565 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDTSHRRAB9A | |
| SCHEMBL20911243 | 0.79 | ALDH1A1 (0.76) | ALDH1A1MAPTHPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108570017-A | The synthesis of 2- amino-4-methylthiazole-5-carboxylates | 西安格瑞德化工新材料有限公司 | 2018-09-25 | — | — | CN | claimed |
| CN-104768377-A | Pesticidal active mixtures comprising anthranilamides | BASF SE | 2015-07-08 | — | — | CN | claimed |
| CN-103664819-A | Preparation method of ethyl 2-amino-4-methylthiazole-5-carboxylate | SHANDONG HUIHAI PHARMACEUTICALS & CHEMICALS CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-103025162-A | Method for cultivating sugar cane | BASF SE | 2013-04-03 | — | — | CN | claimed |
| CN-102079732-B | Method for synthesizing 2-amino-4-methylthiazole-5-carboxylate and derivatives thereof | UNIV XI AN JIAOTONG | 2013-03-13 | — | — | CN | claimed |
| CN-102942565-A | 3,4-dichloro isothiazole derivatives, their preparation method and application | JIANGXI TIANREN ECOLOGY CO LTD | 2013-02-27 | — | — | CN | claimed |
| US-20100273650-A1 | Fungicidal Mixtures Comprising a Substituted 3-Hydroxymethylpyridine and a Further Fungicidal Compound | BASF SE (DE) | 2010-10-28 | — | — | US | claimed |
| US-20100273649-A1 | Fungicidal Mixtures III | BASF SE (DE) | 2010-10-28 | — | — | US | claimed |
| US-20100267555-A1 | Fungicidal mixtures II | BASF SE (DE) | 2010-10-21 | — | — | US | claimed |
| EP-2230909-A2 | FUNGICIDAL MIXTURES COMPRISING A SUBSTITUTED 3-HYDROXYMETHYLPYRIDINE AND A FURTHER FUNGICIDAL COMPOUND | BASF SE (DE) | 2010-09-29 | — | — | EP | claimed |
| WO-2009063074-A2 | FUNGICIDAL MIXTURES I | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063076-A2 | FUNGICIDAL MIXTURES III | BASF SE (DE) | 2009-05-22 | — | — | WO | claimed |
| EP-1515972-B1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | HOFFMANN LA ROCHE (CH) | 2009-05-13 | — | — | EP | claimed |
| WO-2008148859-A2 | FUNGICIDAL MIXTURES | BASF SE (DE) | 2008-12-11 | — | — | WO | claimed |
| WO-2008095890-A2 | FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES | BASF SE (DE) | 2008-08-14 | — | — | WO | claimed |
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |
| CN-1659168-A | Amide-substituted xanthine derivatives having gluconeogenesis modulating activity | HOFFMANN LA ROCHE (CH) | 2005-08-24 | — | — | CN | claimed |
| EP-1515972-A1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-23 | — | — | EP | claimed |
| US-20040014766-A1 | Amide substituted xanthine derivatives | HOFFMANN-LA ROCHE INC. | 2004-01-22 | — | — | US | claimed |
| WO-2003106459-A1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014766-A1 | Amide substituted xanthine derivatives | GYS2, GLS2, PYGL | ALDH1A1 297/4885MAPT 3897/4885HPGD 469/4885 |
| US-20100273649-A1 | Fungicidal Mixtures III | CBR3, CBR1, NOX3 | ALDH1A1 268/4885MAPT 4862/4885HPGD 2184/4885 |
| US-20100267555-A1 | Fungicidal mixtures II | CBR3, CBR1, NOX3 | ALDH1A1 764/4885MAPT 4877/4885HPGD 1430/4885 |
| US-20100273650-A1 | Fungicidal Mixtures Comprising a Substituted 3-Hydroxymethylpyridine and a Further Fungicidal Compound | CBR3, NOX3, CBR1 | ALDH1A1 883/4885MAPT 4861/4885HPGD 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.