SCHEMBL304332

SCHEMBL304332

Cc1nc(N)sc1C(N)=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
MAPT P10636 3/20 0.61
NPC1 O15118 4/20 0.51
RAB9A P51151 2/20 0.51
KMT2A Q03164 1/20 0.51
LCK P06239 1/20 0.50
NOS1 P29475 1/20 0.48
CYP1A2 P05177 2/20 0.45
LMNA P02545 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
POLB P06746 3/20 0.44
UBE2N P61088 3/20 0.44
KDM4E B2RXH2 3/20 0.44
HTT P42858 2/20 0.44
GAA P10253 2/20 0.43
MAPK1 P28482 1/20 0.43
IKBKB O14920 2/20 0.42
LIMK1 P53667 2/20 0.42
PRKACA P17612 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179966 0.83 ALDH1A1 (0.63) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL211474 0.83 ALDH1A1 (0.63) ALDH1A1MAPTNPC1RAB9AKMT2A
Hydrochloric Acid SCHEMBL6239673 0.81 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL21013404 0.81 ALDH1A1 (0.67) ALDH1A1MAPTNPC1RAB9AKMT2A
Hydrochloric Acid SCHEMBL27564569 0.81 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL4602665 0.81 ALDH1A1 (0.61) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL27564565 0.81 ALDH1A1 (0.67) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL1477812 0.80 RAB9A (0.47) ALDH1A1MAPTNPC1RAB9ACYP1A2
SCHEMBL20911243 0.79 ALDH1A1 (0.76) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL299157 0.78 LMNA (0.45) ALDH1A1MAPTNPC1CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160295869-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BAYER CROPSCIENCE LP 2016-10-13 US claimed
CN-104981161-A Composition containing succinate dehydrogenase inhibitor ARCH TIMBER PROTECTION LTD 2015-10-14 CN claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 US claimed
JP-2012500824-A 2012-01-12 JP claimed
JP-2011527306-A 2011-10-27 JP claimed
CN-102137593-A Pesticidal mixtures comprising cyanosulfoximine compounds and spinetoram BASF SE 2011-07-27 CN claimed
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II BASF SE (DE) 2011-06-30 US claimed
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram BASF SE (DE) 2011-06-30 US claimed
CN-102088857-A Pesticidal mixtures comprising isoxazoline compounds ii BASF SE 2011-06-08 CN claimed
EP-2320741-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2011-05-18 EP claimed
CN-101917856-A Combinations comprising a fungicidal strain and an active compound BASF SE 2010-12-15 CN claimed
CN-101909448-A Pesticidal mixtures comprising cyanosulfoximine compounds BASF SE 2010-12-08 CN claimed
EP-2219456-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2010-08-25 EP claimed
US-20100209410-A1 Combinations Comprising a Fungicidal Strain and an Active Compound BASF SE (DE) 2010-08-19 US claimed
EP-2192841-A2 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AT LEAST ONE ADDITIONAL FUNGICIDE Basf Se (DE) 2010-06-09 EP claimed
WO-2010023171-A2 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS AND SPINETORAM BASF SE (DE) 2010-03-04 WO claimed
WO-2010003877-A1 PESTICIDAL MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS II BASF SE (DE) 2010-01-14 WO claimed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 WO claimed
WO-2009037242-A2 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BASF SE (DE) 2009-03-26 WO claimed
WO-2009007233-A2 PESTICIDAL MIXTURES COMPRISING SULFONAMIDES AND ONE OR MORE FUNGICIDES BASF SE (DE) 2009-01-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110159107-A1 Pesticidal Mixtures Comprising Isoxazoline Compounds II PRDX1, PRDX2, PRDX5 ALDH1A1 1811/4885MAPT 3866/4885NPC1 3022/4885
US-20100209410-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL ALDH1A1 3122/4885MAPT 3701/4885NPC1 4277/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS ALDH1A1 2499/4885MAPT 4646/4885NPC1 3572/4885
US-20160295869-A1 Combinations Comprising a Fungicidal Strain and an Active Compound O60361, SPOUT1, FBL ALDH1A1 3142/4885MAPT 3739/4885NPC1 4061/4885
US-20110160054-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds and Spinetoram CHRM3, CHRM2, BRS3 ALDH1A1 3669/4885MAPT 3290/4885NPC1 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.