Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997454 | 0.90 | RAPGEF4 (0.43) | RAPGEF4PTGS2LMNAMEN1MAPT | |
| SCHEMBL17997453 | 0.89 | RAPGEF4 (0.42) | RAPGEF4PTGS2LMNAMEN1MAPT | |
| SCHEMBL17997452 | 0.88 | PTGS2 (0.57) | PTGS2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17997442 | 0.87 | PTGS2 (0.56) | PTGS2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17997449 | 0.86 | PTGS2 (0.48) | RAPGEF4PTGS2MEN1MAPTKMT2A | |
| SCHEMBL17997476 | 0.85 | PTGS2 (0.49) | PTGS2LMNAMEN1MAPTKMT2A | |
| SCHEMBL17997457 | 0.84 | PTGS2 (0.50) | PTGS2LMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL17997464 | 0.83 | PTGS2 (0.44) | PTGS2LMNAMEN1MAPTCRHBP | |
| SCHEMBL2528716 | 0.82 | PTGS2 (0.59) | PTGS2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL13007202 | 0.82 | PTGS2 (0.51) | RAPGEF4PTGS2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |