Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004377 | 0.91 | CTSS (0.38) | NOTUMCTSSCTSKIKBKBDAO | |
| SCHEMBL18003986 | 0.91 | IDH1 (0.36) | NOTUMCTSSCTSKDAO | |
| SCHEMBL18004255 | 0.90 | POLB (0.37) | CTSSCTSKDAO | |
| SCHEMBL18004215 | 0.88 | NOTUM (0.41) | NOTUMCTSSCTSKSHMT1IKBKB | |
| SCHEMBL26070226 | 0.88 | NOTUM (0.44) | NOTUMCTSSCTSKIKBKB | |
| SCHEMBL18004508 | 0.85 | NOTUM (0.35) | NOTUMCTSSCTSKIKBKB | |
| SCHEMBL18004264 | 0.84 | RXRA (0.36) | CTSSCTSKDAO | |
| SCHEMBL18004163 | 0.84 | QPCT (0.32) | NOTUM | |
| SCHEMBL18004375 | 0.83 | MEN1 (0.37) | CTSSCTSKDAO | |
| SCHEMBL18004177 | 0.83 | MRGPRX4 (0.33) | NOTUMCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | NOTUM 1379/4885CTSS 2273/4885CTSK 2390/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | NOTUM 1379/4885CTSS 2273/4885CTSK 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.