Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005574 | 0.96 | GRM5 (0.40) | GRM5MDM2TNKSPARP2PARP1 | |
| SCHEMBL18005397 | 0.96 | GRM5 (0.40) | GRM5MDM2TNKSPARP2PARP1 | |
| SCHEMBL18005328 | 0.95 | MDM2 (0.41) | GRM5MDM2TNKSPARP2PARP1 | |
| SCHEMBL18005301 | 0.91 | ALOX15 (0.41) | GRM5ALOX15KDM4EALDH1A1RAB9A | |
| SCHEMBL18005351 | 0.91 | KDM1A (0.33) | GRM5METKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18005300 | 0.88 | ALOX15 (0.34) | GRM5ALOX15KDM4EALDH1A1RAB9A | |
| SCHEMBL18005355 | 0.88 | NOTUM (0.34) | GRM5TGFBR1KDM4EALDH1A1RAB9A | |
| SCHEMBL18005487 | 0.87 | ALDH1A1 (0.39) | ALOX15KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL18005576 | 0.87 | KDM1A (0.32) | GRM5MDM2KDM4EALDH1A1RAB9A | |
| SCHEMBL16399641 | 0.86 | GRM5 (0.43) | GRM5ALOX15KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | GRM5 1425/4885MDM2 4295/4885TNKS 3528/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | GRM5 1425/4885MDM2 4295/4885TNKS 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.