Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26070926 | 0.84 | TTK (0.52) | TTKCHEK1HPGDHSD17B10KDM4E | |
| SCHEMBL18006339 | 0.82 | HPGD (0.35) | TTKHPGDKDM4ECYP11B1CYP11B2 | |
| SCHEMBL18006382 | 0.80 | CHEK1 (0.49) | CHEK1HPGDHSD17B10KDM4ECYP11B1 | |
| SCHEMBL18006387 | 0.80 | KDM4E (0.41) | KDM4ECYP11B1CYP11B2ALDH1A1MAPK1 | |
| SCHEMBL18004881 | 0.79 | GPR84 (0.39) | KDM4ECYP11B1CYP11B2MAPT | |
| SCHEMBL18006354 | 0.79 | SIRT2 (0.40) | CYP11B1CYP11B2TP53MAPT | |
| SCHEMBL18006428 | 0.78 | LMNA (0.43) | TDP1CYP11B1CYP11B2CYP2D6MAPK1 | |
| SCHEMBL18006388 | 0.78 | SIRT2 (0.39) | KDM4ECYP11B1CYP11B2ALDH1A1MEN1 | |
| SCHEMBL18006355 | 0.78 | MAOB (0.39) | HPGDKDM4EPOLBRXFP1ALDH1A1 | |
| SCHEMBL18006386 | 0.78 | EGFR (0.39) | KDM4ECYP11B1CYP11B2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | TTK 1381/4885CHEK1 923/4885HPGD 2152/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | TTK 1381/4885CHEK1 923/4885HPGD 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.