Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.56 |
| ▸ | CDK8 | P49336 | 5/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | FLT3 | P36888 | 7/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263731 | 0.83 | KDR (0.61) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL14365346 | 0.83 | RIPK1 (0.65) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL28504617 | 0.79 | FGFR1 (0.67) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL19891723 | 0.79 | KDR (0.62) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL4831501 | 0.76 | CDK8 (0.81) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL858559 | 0.76 | RIPK1 (0.58) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL15871324 | 0.75 | RIPK1 (0.71) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL14365329 | 0.75 | RIPK1 (0.61) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL13854149 | 0.75 | RIPK1 (0.61) | RIPK1CDK8AXLFLT3PIK3CD | |
| SCHEMBL21045468 | 0.74 | FLT3 (0.52) | RIPK1CDK8FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190288213-A1 | SYSTEMS BASED ON 5-BROMO-7-AZAINDOLE DERIVATIVES AS FUTURE SOLID EMITTERS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2019-09-19 | — | — | US | disclosed |
| EP-3466947-A1 | SYSTEMS BASED ON 5-BROMO-7-AZAINDOLE DERIVATIVES AS FUTURE SOLID EMITTERS | Consejo Superior De Investigaciones Científicas (ES) | 2019-04-10 | — | — | EP | disclosed |
| WO-2016132006-A1 | ORGANOGEL BASED ON SELF-ASSEMBLED 5-(4-NONYLPHENYL)-7-AZAINDOLES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2016-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190288213-A1 | SYSTEMS BASED ON 5-BROMO-7-AZAINDOLE DERIVATIVES AS FUTURE SOLID EMITTERS | AOX1, BRI3BP, ALDH1A2 | RIPK1 4002/4885CDK8 1315/4885AXL 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.