Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP13 | P45452 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1800798 | 1.00 | MMP1 (0.48) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1796951 | 0.86 | MMP1 (0.60) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1796948 | 0.86 | MMP1 (0.60) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1798306 | 0.86 | MMP1 (0.49) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1798308 | 0.86 | MMP1 (0.49) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1797575 | 0.78 | MMP2 (0.43) | MMP13MMP9MMP2 | |
| SCHEMBL4373478 | 0.77 | F2 (0.48) | MMP9MMP2 | |
| SCHEMBL1802359 | 0.76 | MMP2 (0.43) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1798952 | 0.76 | ADAMTS7 (0.45) | MMP1MMP13MMP9ADAM17MMP2 | |
| SCHEMBL1798953 | 0.76 | ADAMTS7 (0.45) | MMP1MMP13MMP9ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951972-B2 | Human adam-10 inhibitors | EXELIXIS, INC. (US) | 2011-05-31 | — | — | US | disclosed |