Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.46 |
| ▸ | ANPEP | P15144 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009287 | 0.88 | SLC6A3 (0.37) | MMP2SLC6A3ALDH1A1HTTMAPT | |
| SCHEMBL18009188 | 0.84 | FKBP1A (0.45) | MMP2ALDH1A1 | |
| SCHEMBL18009458 | 0.83 | MMP2 (0.54) | MMP2ANPEPALDH1A1 | |
| SCHEMBL18009450 | 0.81 | ATM (0.47) | MMP2ANPEPALDH1A1MAPTKDM4E | |
| SCHEMBL18009294 | 0.80 | MMP2 (0.46) | MMP2ANPEPALDH1A1HTTMAPT | |
| SCHEMBL18009337 | 0.78 | MMP2 (0.42) | MMP2ANPEP | |
| SCHEMBL18009336 | 0.78 | MMP2 (0.42) | MMP2ANPEPALDH1A1HTT | |
| SCHEMBL18009463 | 0.77 | MMP2 (0.42) | MMP2ANPEP | |
| SCHEMBL18009202 | 0.77 | MMP2 (0.42) | MMP2ANPEP | |
| SCHEMBL18009292 | 0.76 | PIK3CD (0.41) | MMP2ALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |