Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009190 | 0.88 | MMP2 (0.46) | SLC6A3KDM4EMMP2ALDH1A1MAPT | |
| SCHEMBL18009303 | 0.85 | FKBP1A (0.43) | ACEALDH1A1 | |
| SCHEMBL18009194 | 0.84 | PEPD (0.39) | MMP2AGTR2ALDH1A1 | |
| SCHEMBL18009192 | 0.82 | PIK3CD (0.36) | AGTR2ACE | |
| SCHEMBL18009372 | 0.81 | PIK3CD (0.34) | MMP2 | |
| SCHEMBL18009375 | 0.79 | PIK3CD (0.33) | ELANE | |
| SCHEMBL18009388 | 0.79 | PEPD (0.34) | ACE | |
| SCHEMBL18007441 | 0.79 | PIN1 (0.35) | — | |
| SCHEMBL18009300 | 0.77 | PIK3CD (0.42) | MMP2ALDH1A1MAPTHTT | |
| SCHEMBL18009294 | 0.77 | MMP2 (0.46) | MMP2ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |