Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 9/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009188 | 0.89 | FKBP1A (0.45) | FKBP1ACTSLHCAR2ALDH1A1CYP1A2 | |
| SCHEMBL18009287 | 0.85 | SLC6A3 (0.37) | ACEALDH1A1 | |
| SCHEMBL18009388 | 0.83 | PEPD (0.34) | ACEHCAR2 | |
| SCHEMBL18009194 | 0.82 | PEPD (0.39) | HCAR2ALDH1A1 | |
| SCHEMBL18009192 | 0.80 | PIK3CD (0.36) | ACEHCAR2 | |
| SCHEMBL18009372 | 0.79 | PIK3CD (0.34) | HCAR2 | |
| SCHEMBL18009375 | 0.77 | PIK3CD (0.33) | HCAR2 | |
| SCHEMBL18009283 | 0.77 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL18007441 | 0.76 | PIN1 (0.35) | HCAR2 | |
| SCHEMBL18009300 | 0.75 | PIK3CD (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |