Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949417 | 0.84 | KCNA5 (0.45) | — | |
| SCHEMBL18015897 | 0.82 | CYP11B2 (0.47) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL13615055 | 0.77 | CYP11B2 (0.56) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL18014699 | 0.76 | KIF11 (0.47) | KIF11FFAR1 | |
| SCHEMBL13872997 | 0.76 | PTGS2 (0.43) | FFAR1 | |
| SCHEMBL18014710 | 0.75 | KIF11 (0.53) | KIF11CYP11B2CYP11B1FFAR1 | |
| SCHEMBL20343043 | 0.74 | CYP11B2 (0.54) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL18601376 | 0.73 | KIF11 (0.59) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL278624 | 0.71 | IDO1 (0.52) | — | |
| SCHEMBL5336630 | 0.71 | DPP4 (0.54) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229847-A1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | PFIZER (US) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229847-A1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | BACE1, BACE2, PSEN2 | KIF11 4539/4885CYP11B2 1903/4885CYP11B1 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.