Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5419030 | 0.90 | APP (0.35) | — | |
| SCHEMBL5433620 | 0.88 | APP (0.34) | — | |
| SCHEMBL5420431 | 0.87 | APP (0.33) | — | |
| SCHEMBL5418493 | 0.87 | APP (0.33) | — | |
| Sulfuric Acid SCHEMBL2854050 | 0.82 | CYP1A2 (0.36) | — | |
| Sulfuric Acid SCHEMBL8919999 | 0.81 | CYP1A2 (0.35) | — | |
| Sulfuric Acid SCHEMBL5493743 | 0.81 | — | — | |
| SCHEMBL6068676 | 0.80 | — | — | |
| SCHEMBL5416172 | 0.79 | CDK1 (0.32) | — | |
| SCHEMBL2923881 | 0.78 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345580-B9 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2009-11-25 | — | — | EP | claimed |
| EP-1345580-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-1345579-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING AN AMINO PYRAZOLE AND A MINERAL COMPOUND | OREAL (FR) | 2005-06-29 | — | — | EP | claimed |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | L'OREAL (FR) | 2004-12-02 | — | — | US | claimed |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | L'OREAL (FR) | 2004-05-13 | — | — | US | claimed |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | L'OREAL (FR) | 2004-04-22 | — | — | US | claimed |
| US-7951209-B2 | device comprises at least three compartments, a first compartment that contains the carbonyl compound that is useful for the invention, a second compartment that contains a diaminopyrazole, and a third compartment that contains an oxidizing composition | L'OREAL (FR) | 2011-05-31 | — | — | US | disclosed |
| US-20080141468-A1 | device comprises at least three compartments, a first compartment that contains the carbonyl compound that is useful for the invention, a second compartment that contains a diaminopyrazole, and a third compartment that contains an oxidizing composition | L'OREAL (FR) | 2008-06-19 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-20070050924-A1 | Composition for the oxidation dyeing of keratin fibres, comprising at least one 4,5- or 3,4-diaminopyrazole or a triaminopyrazole and at least one particular cellulose-based compound, and dyeing process | L'OREAL (US) | 2007-03-08 | — | — | US | disclosed |
| US-7153330-B2 | Composition for the oxidation dyeing of keratin fibres, comprising at least one 4,5- or 3,4-diaminopyrazole or a triaminopyrazole and at least one selected mineral compound, and dyeing process | L'OREAL (FR) | 2006-12-26 | — | — | US | disclosed |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | L'OREAL (FR) | 2004-12-02 | — | — | US | disclosed |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | L'OREAL (FR) | 2004-05-13 | — | — | US | disclosed |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | L'OREAL (FR) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070050924-A1 | Composition for the oxidation dyeing of keratin fibres, comprising at least one 4,5- or 3,4-diaminopyrazole or a triaminopyrazole and at least one particular cellulose-based compound, and dyeing process | KRT18, TUBB3, COX5A | LMNA 1710/4885SLC6A6 3072/4885CYP2C19 637/4885 |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | KRT18, TUBB3, PPOX | LMNA 1906/4885SLC6A6 3659/4885CYP2C19 553/4885 |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | KRT18, TUBB3, COX5A | LMNA 2105/4885SLC6A6 3457/4885CYP2C19 450/4885 |
| US-20080141468-A1 | device comprises at least three compartments, a first compartment that contains the carbonyl compound that is useful for the invention, a second compartment that contains a diaminopyrazole, and a third compartment that contains an oxidizing composition | KRT18, NDUFB5, NDUFB3 | LMNA 2183/4885SLC6A6 3398/4885CYP2C19 489/4885 |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | KRT18, TUBB3, COX5A | LMNA 1846/4885SLC6A6 3721/4885CYP2C19 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.