Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631768 | 0.86 | EPHX2 (0.44) | EPHX2SMN1; SMN2DRD3DRD2DRD4 | |
| SCHEMBL18022786 | 0.76 | DNMT1 (0.46) | EPHX2DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL18022785 | 0.76 | DNMT1 (0.46) | EPHX2DNMT1DNMT3LDNMT3AMEN1 | |
| SCHEMBL16631777 | 0.72 | MAPT (0.46) | KMT2ANPSR1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL13278990 | 0.70 | HTR1A (0.68) | DRD3DRD2HTR1A | |
| SCHEMBL13469516 | 0.70 | HTR1A (0.68) | DRD3DRD2HTR1A | |
| SCHEMBL13469642 | 0.70 | HTR1A (0.68) | DRD3DRD2HTR1A | |
| SCHEMBL16631776 | 0.68 | EPHX2 (0.44) | EPHX2SMN1; SMN2DRD3HTR1AHTR2A | |
| SCHEMBL28431822 | 0.68 | KDM4E (0.46) | EPHX2SMN1; SMN2 | |
| SCHEMBL463093 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160235870-A1 | MULTIFUNCTIONAL CHELATORS, COMPLEXES, AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235870-A1 | MULTIFUNCTIONAL CHELATORS, COMPLEXES, AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME | FECH, SLC40A1, TFRC | EPHX2 2976/4885DNMT1 2122/4885DNMT3L 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.