Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022786 | 0.91 | DNMT1 (0.46) | DNMT1DNMT3LDNMT3ARAB9ACYP1A2 | |
| SCHEMBL18022784 | 0.76 | KDM4E (0.50) | SCN9ACYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL18022787 | 0.76 | EPHX2 (0.43) | DNMT1DNMT3LDNMT3AKMT2AMEN1 | |
| SCHEMBL3455770 | 0.75 | DNMT1 (0.62) | DNMT1DNMT3LDNMT3ARAB9ACYP1A2 | |
| SCHEMBL17060904 | 0.73 | KDM4E (0.49) | SCN9ARAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL21851995 | 0.72 | KMT2A (0.58) | RAB9ACYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL21449812 | 0.70 | RAB9A (0.44) | DNMT1DNMT3LDNMT3ARAB9ACYP3A4 | |
| SCHEMBL21362830 | 0.70 | HPGDS (0.45) | SCN9ARAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL24795948 | 0.69 | MEN1 (0.58) | KMT2AMEN1NPSR1ALDH1A1HDAC8 | |
| SCHEMBL21480866 | 0.69 | KMT2A (0.58) | CYP1A2CYP3A4KDM4ECYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10441669-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2019-10-15 | — | — | US | disclosed |
| US-20160235870-A1 | MULTIFUNCTIONAL CHELATORS, COMPLEXES, AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235870-A1 | MULTIFUNCTIONAL CHELATORS, COMPLEXES, AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME | FECH, SLC40A1, TFRC | DNMT1 2122/4885DNMT3L 3832/4885DNMT3A 2958/4885 |
| US-10441669-B2 | Multifunctional chelators, complexes, and compositions thereof, and methods of using same | FECH, SLC40A1, TFRC | DNMT1 2122/4885DNMT3L 3832/4885DNMT3A 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.