Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645383 | 0.87 | PTPN11 (0.44) | CYP17A1PTPN11ADAMTS4NPC1RAB9A | |
| SCHEMBL8575829 | 0.82 | KMT2A (0.63) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL22019039 | 0.82 | MAPT (0.37) | PTPN11MAPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL26079042 | 0.81 | CYP17A1 (0.50) | CYP17A1PTPN11ADAMTS4NPC1RAB9A | |
| SCHEMBL25870990 | 0.81 | CYP17A1 (0.50) | CYP17A1PTPN11MAPTPSMB8NAMPT | |
| SCHEMBL627043 | 0.81 | ALDH1A1 (0.53) | CYP17A1PTPN11MAPTADAMTS4NPC1 | |
| SCHEMBL254714 | 0.80 | PTPN11 (0.51) | CYP17A1PTPN11PSMB8NAMPTMAPKAPK2 | |
| SCHEMBL2040098 | 0.80 | KMT2A (0.65) | MAPTRAB9ASMN1; SMN2MEN1LMNA | |
| SCHEMBL23817020 | 0.80 | CYP17A1 (0.48) | CYP17A1ADAMTS4MAP4K4FAAH | |
| SCHEMBL3335259 | 0.79 | FAAH (0.62) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988492-B2 | Methods for post-fabrication functionalization of poly(ester ureas) | THE UNIVERSITY OF AKRON (US) | 2018-06-05 | — | — | US | disclosed |
| US-20160237212-A1 | METHODS FOR POST-FABRICATION FUNCTIONALIZATION OF POLY(ESTER UREAS) | THE UNIVERSITY OF AKRON (US) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237212-A1 | METHODS FOR POST-FABRICATION FUNCTIONALIZATION OF POLY(ESTER UREAS) | PTMS, MUSK, DSTYK | CYP17A1 3077/4885PTPN11 2864/4885MAPT 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.