Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18025366 | 0.82 | CYP17A1 (0.47) | MAPTKMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11649697 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1KMT2ALMNANLRP1 | |
| SCHEMBL4929584 | 0.79 | MIF (0.44) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL5864432 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL11650332 | 0.78 | SMN1; SMN2 (0.44) | MAPTALDH1A1KMT2ALMNAMAPK1 | |
| SCHEMBL9027360 | 0.77 | LMNA (0.48) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL5664612 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1KMT2ALMNACA12 | |
| SCHEMBL10126608 | 0.71 | CA12 (0.55) | CA12CA1CA2CA9PTPN11 | |
| SCHEMBL12837653 | 0.71 | CTSS (0.52) | ALDH1A1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL14645383 | 0.71 | PTPN11 (0.44) | ALDH1A1KMT2ALMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660968-B2 | Spirocyclic degronimers for target protein degradation | C4 THERAPEUTICS, INC. (US) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660968-B2 | Spirocyclic degronimers for target protein degradation | STUB1, UBE3C, UBE3A | MAPT 2629/4885ALDH1A1 2438/4885GAA 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.