Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18030938 | 0.84 | IMPDH2 (0.46) | ALKBH5FTOIMPDH2GPR3EGFR | |
| SCHEMBL17032702 | 0.80 | ALKBH5 (0.58) | ALKBH5FTOIMPDH2GPR3EGFR | |
| SCHEMBL21030544 | 0.78 | ALKBH5 (0.65) | ALKBH5FTOGPR3KDM4EMAPT | |
| SCHEMBL18055742 | 0.77 | MAPT (0.45) | ALKBH5FTOIMPDH2KDM4EMAPT | |
| SCHEMBL18055746 | 0.74 | ALKBH5 (0.42) | ALKBH5FTOIMPDH2KDM4EMAPT | |
| SCHEMBL18030940 | 0.73 | GPR3 (0.57) | ALKBH5FTOIMPDH2GPR3EGFR | |
| SCHEMBL18028321 | 0.73 | GPR3 (0.52) | ALKBH5FTOIMPDH2GPR3EGFR | |
| SCHEMBL18030949 | 0.73 | EGFR (0.51) | ALKBH5FTOIMPDH2GPR3EGFR | |
| SCHEMBL26297015 | 0.73 | ALKBH5 (0.49) | ALKBH5FTOGPR3KDM4EMAPT | |
| SCHEMBL18030937 | 0.72 | KDM4E (0.50) | ALKBH5FTOIMPDH2GPR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170098781-A1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | DBF4, DDT, SLC43A3 | ALKBH5 1111/4885FTO 509/4885IMPDH2 1250/4885 |
| US-20160248026-A1 | NITRILE SUBSTITUTED DIBENZOFURANS | DBF4, NXF1, NCF1 | ALKBH5 601/4885FTO 426/4885IMPDH2 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.