SCHEMBL18030

SCHEMBL18030

N/C(=N\O)c1nccc(-c2cccc(C(F)(F)F)c2)n1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 7/20 0.67
CTSS P25774 1/20 0.45
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 1/20 0.43
KDM1A O60341 2/20 0.43
CCNT1 O60563 1/20 0.43
CCNA2 P20248 1/20 0.43
CDK2 P24941 1/20 0.43
CDK9 P50750 1/20 0.43
XDH P47989 1/20 0.42
PIK3CD O00329 1/20 0.41
PIK3CA P42336 1/20 0.41
PIK3CG P48736 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
PARP1 P09874 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18031 1.00 KMO (0.67) KMOCTSSKDM4EALDH1A1KDM1A
SCHEMBL12439744 0.79 KMO (0.45) KMOKDM4EALDH1A1HTR3EHTR3B
SCHEMBL1935591 0.79 KMO (0.45) KMOKDM4EALDH1A1HTR3EHTR3B
SCHEMBL18032 0.77 KMO (0.67) KMOCTSSKDM4EALDH1A1KDM1A
SCHEMBL2788482 0.76 CCNT1 (0.63) KMOCTSSKDM4EALDH1A1KDM1A
SCHEMBL7426086 0.74 ALDH1A1 (0.51) CTSSKDM4EALDH1A1XDH
SCHEMBL18343 0.74 KMO (0.65) KMOALDH1A1CDK2
SCHEMBL18342 0.74 KMO (0.65) KMOALDH1A1CDK2
SCHEMBL11469890 0.74 KMO (0.62) KMOCTSSKDM4EALDH1A1KDM1A
SCHEMBL13273287 0.74 KMO (0.62) KMOCTSSKDM4EALDH1A1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed