Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.65 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343 | 1.00 | KMO (0.65) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL18344 | 0.77 | KMO (0.67) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL935401 | 0.75 | KMO (0.60) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL27964563 | 0.75 | CYP1A2 (0.69) | KMOCYP1A2CYP3A4HSD17B10ALOX15 | |
| SCHEMBL1934839 | 0.74 | SCN9A (0.48) | KMOCYP1A2CYP3A4TSHRMAPK1 | |
| SCHEMBL12439746 | 0.74 | SCN9A (0.48) | KMOCYP1A2CYP3A4TSHRMAPK1 | |
| SCHEMBL18031 | 0.74 | KMO (0.67) | KMOCDK2ALDH1A1 | |
| SCHEMBL18030 | 0.74 | KMO (0.67) | KMOCDK2ALDH1A1 | |
| SCHEMBL17609 | 0.73 | ADRB1 (0.36) | NPC1GAARAB9AKMT2A | |
| SCHEMBL17608 | 0.73 | ADRB1 (0.36) | NPC1GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |