Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18030 | 0.77 | KMO (0.67) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL18031 | 0.77 | KMO (0.67) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL18344 | 0.75 | KMO (0.67) | KMOCDK2ALDH1A1CLK4 | |
| SCHEMBL7426082 | 0.74 | MEN1 (0.51) | CTSSIDO1KDM4EALDH1A1 | |
| SCHEMBL11469890 | 0.74 | KMO (0.62) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL13273287 | 0.74 | KMO (0.62) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL2788482 | 0.74 | CCNT1 (0.63) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL21116043 | 0.73 | CSNK1A1 (0.58) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL11468072 | 0.73 | KMO (0.58) | KMOCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL17610 | 0.71 | HDAC4 (0.38) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |