Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.34 |
| ▸ | MLYCD | O95822 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776384 | 0.87 | NR1H3 (0.39) | LMNANR1H3NR1H2MLYCD | |
| SCHEMBL21776385 | 0.86 | LMNA (0.43) | LMNANR1H3NR1H2MLYCDSMN1; SMN2 | |
| SCHEMBL21943829 | 0.85 | ELANE (0.33) | — | |
| SCHEMBL21776168 | 0.85 | LMNA (0.36) | LMNANR1H3NR1H2MLYCDSMN1; SMN2 | |
| SCHEMBL18610621 | 0.84 | MLYCD (0.36) | LMNANR1H3NR1H2MLYCDSMN1; SMN2 | |
| SCHEMBL24859820 | 0.82 | ELANE (0.30) | — | |
| SCHEMBL21776170 | 0.82 | NPSR1 (0.33) | LMNANR1H3NR1H2MAPK1NPSR1 | |
| SCHEMBL11913011 | 0.78 | ELANE (0.37) | LMNANR1H3NR1H2MLYCDSMN1; SMN2 | |
| SCHEMBL21776169 | 0.78 | KCNJ11 (0.38) | GAANPSR1 | |
| SCHEMBL9973369 | 0.74 | ELANE (0.34) | LMNANR1H3NR1H2MLYCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016132247-A1 | FLUORO-ALCOHOL ADDITIVES FOR ORIENTATION CONTROL OF BLOCK COPOLYMERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-08-25 | — | — | WO | disclosed |