SCHEMBL180318

SCHEMBL180318

CCCCCCCCCCCCCCCC(=O)OC1CC(=O)NC1=O

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.49
NAAA Q02083 4/20 0.49
DGKA P23743 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628006 1.00 PRKCA (0.49) PRKCANAAADGKA
SCHEMBL2099423 0.98 PRKCA (0.47) PRKCANAAADGKA
SCHEMBL20589363 0.92 PRKCA (0.38) PRKCANAAA
SCHEMBL1517935 0.91 PRKCA (0.41) PRKCANAAADGKA
SCHEMBL6551912 0.88 HSD17B10 (0.39) PRKCA
SCHEMBL371437 0.87 CNR2 (0.41) PRKCANAAADGKA
SCHEMBL977159 0.84 MAP3K14 (0.38)
SCHEMBL9682839 0.84 PRKCA (0.33) PRKCANAAA
SCHEMBL10727648 0.82 ADRA1A (0.42) PRKCA
SCHEMBL10877677 0.81 GPR84 (0.43) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3084442-B1 DIAGNOSTIC REAGENTS FOR IMPROVED IN VIVO OR IN VITRO CELL-MEDIATED IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS STATENS SERUMINSTITUT (DK) 2021-03-17 EP disclosed
US-10641770-B2 Diagnostic reagents for improved in vivo or in vitro cell-mediated immunological diagnosis of tuberculosis STATENS SERUM INSTITUT (DK) 2020-05-05 US disclosed
EP-2912056-B1 M. TUBERCULOSIS VACCINES STATENS SERUMINSTITUT (DK) 2020-02-12 EP disclosed
EP-3134116-B1 NEW M.TUBERCULOSIS VACCINES STATENS SERUMINSTITUT (DK) 2019-04-03 EP disclosed
US-10245313-B2 DNA motif compounds and methods for inducing specific antibodies and cellular immunity VERSITECH LIMITED (CN) 2019-04-02 US disclosed
EP-2421557-B1 A TUBERCULOSIS TB VACCINE TO PREVENT REACTIVATION STATENS SERUMINSTITUT (DK) 2018-12-05 EP disclosed
US-10004793-B2 M.tuberculosis vaccines STATENS SERUM INSTITUT (DK) 2018-06-26 US disclosed
EP-3209784-A1 DNA MOTIF COMPOUNDS AND METHODS FOR INDUCING SPECIFIC ANTIBODIES AND CELLULAR IMMUNITY Versitech Limited (CN) 2017-08-30 EP disclosed
EP-2163255-B1 Tuberculosis vaccines comprising antigens expressed during the latent infection phase STATENS SERUMINSTITUT (DK) 2017-08-09 EP disclosed
EP-3134116-A1 NEW M.TUBERCULOSIS VACCINES Statens Serum Institut (DK) 2017-03-01 EP disclosed
WO-2005061534-A2 IMPROVED TUBERCULOSIS VACCINES STATENS SERUM INSTITUT (DK) 2005-07-07 WO disclosed
EP-1523331-A2 THERAPEUTIC TB VACCINE Statens Serum Institut (DK) 2005-04-20 EP disclosed
WO-2004099771-A1 A NEW SPECIFIC EPITOPE BASED IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS STATENS SERUM INSTITUT (DK) 2004-11-18 WO disclosed
US-20040057963-A1 Therapeutic TB vaccine STATENS SERUM INSTITUTE (DK) 2004-03-25 US disclosed
WO-2004006952-A2 THERAPEUTIC TUBERCULOSIS VACCINES STATENS SERUM INSTITUT (DK) 2004-01-22 WO disclosed
US-20040013685-A1 Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis STATENS SERUM INSTITUT (DK) 2004-01-22 US disclosed
US-20030147897-A1 M. tuberculosis antigens STATENS SERUM INSTITUT (DK) 2003-08-07 US disclosed
EP-1278769-A2 TUBERCULOSIS ANTIGENS AND METHODS OF USE THEREOF Statens Serum Institut (DK) 2003-01-29 EP disclosed
US-20020176867-A1 Hybrids of M. tuberculosis antigens ANDERSEN PETER (DK) 2002-11-28 US disclosed
WO-2001079274-A2 TUBERCULOSIS ANTIGENS AND METHODS OF USE THEREOF STATENS SERUM INSTITUT (DK) 2001-10-25 WO disclosed