SCHEMBL2099423

SCHEMBL2099423

CCCCCC(=O)OC1CC(=O)NC1=O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.47
NAAA Q02083 2/20 0.46
DGKA P23743 1/20 0.42
NPC1 O15118 1/20 0.40
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180318 0.98 PRKCA (0.49) PRKCANAAADGKA
SCHEMBL3628006 0.98 PRKCA (0.49) PRKCANAAADGKA
SCHEMBL1517935 0.92 PRKCA (0.41) PRKCANAAADGKANPC1CYP19A1
SCHEMBL20589363 0.91 PRKCA (0.38) PRKCANAAACYP19A1
SCHEMBL6551912 0.89 HSD17B10 (0.39) PRKCANPC1CYP19A1
SCHEMBL371437 0.86 CNR2 (0.41) PRKCANAAADGKA
SCHEMBL977159 0.85 MAP3K14 (0.38) NPC1CYP19A1
SCHEMBL9682839 0.85 PRKCA (0.33) PRKCANAAANPC1
SCHEMBL10480498 0.82 PRKCA (0.32) PRKCA
SCHEMBL11095324 0.82 NPC1 (0.36) PRKCANPC1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3180432-A1 LIBRARY GENERATION FOR NEXT-GENERATION SEQUENCING Abbott Molecular Inc. (US) 2017-06-21 EP disclosed
WO-2016025872-A1 LIBRARY GENERATION FOR NEXT-GENERATION SEQUENCING ABBOTT MOLECULAR INC. (US) 2016-02-18 WO disclosed
US-20160046987-A1 LIBRARY GENERATION FOR NEXT-GENERATION SEQUENCING ABBOTT MOLECULAR INC. 2016-02-18 US disclosed
EP-2106812-B1 Methods of Making and Using Surfactant Polymers NANOMIMETICS INC (US) 2016-01-13 EP disclosed
US-9125969-B2 Methods of making and using surfactant polymers NANOMIMETICS, INC. (US) 2015-09-08 US disclosed
US-20120245288-A1 METHODS OF MAKING AND USING SURFACTANT POLYMERS NANOMIMETICS, INC. (US) 2012-09-27 US disclosed
WO-2006132446-A9 METHOD OF MANUFACTURING PROBE-IMMOBILIZED CARRIER CANON KABUSHIKI KAISHA (JP) 2012-09-13 WO disclosed
US-8163302-B2 Methods of making and using surfactant polymers NANOMIMETICS, INC. (US) 2012-04-24 US disclosed
EP-2106812-A2 Methods of Making and Using Surfactant Polymers NanoMimetics, Inc. (US) 2009-10-07 EP disclosed
US-20090191566-A1 Kits for Isolating Nucleic Acids Using Multifunctional Group-Coated Solid Phase Carriers AGENCOURT BIOSCIENCE CORPORATION (US) 2009-07-30 US disclosed
US-7276474-B2 Methods of making and using surfactant polymers NANOMIMETICS, INC. (US) 2007-10-02 US disclosed
EP-1776458-A2 METHODS OF ISOLATING NUCLEIC ACIDS USING MULTIFUNCTIONAL GROUP-COATED SOLID PHASE CARRIERS Agencourt Bioscience Corporation (US) 2007-04-25 EP disclosed
WO-2006132446-A1 METHOD OF MANUFACTURING PROBE-IMMOBILIZED CARRIER CANON KABUSHIKI KAISHA (JP) 2006-12-14 WO disclosed
US-20060177836-A1 Methods of isolating nucleic acids using multifunctional group-coated solid phase carriers AGENCOURT BIOSCIENCE CORPORATION 2006-08-10 US disclosed
WO-2006015326-A2 METHODS OF ISOLATING NUCLEIC ACIDS USING MULTIFUNCTIONAL GROUP-COATED SOLID PHASE CARRIERS AGENCOURT BIOSCIENCE CORPORATION (US) 2006-02-09 WO disclosed
US-20050008603-A1 Methods of making and using surfactant polymers NANOMIMETICS, INC. 2005-01-13 US disclosed
US-6759388-B1 COMBLIKE POLYMERS; INCREASING BLOOD BIOCOMPATIBILITY OF IMPLANTS; SUCH AS OLIGOSACCHARIDE OR OLIGOPEPTIDE SIDE CHAIN DERIVATIZED POLYVINYL AMIDE, POLYVINYL ALCOHOL OR POLYLYSINE NANOMIMETICS, INC. 2004-07-06 US disclosed
EP-1086149-A4 SURFACTANTS THAT MIMIC THE GLYCOCALYX MARCHANT ROGER E (US) 2002-10-30 EP disclosed
EP-1086149-A1 SURFACTANTS THAT MIMIC THE GLYCOCALYX Marchant, Roger E. (US) 2001-03-28 EP disclosed
WO-1999055742-A1 SURFACTANTS THAT MIMIC THE GLYCOCALYX MARCHANT ROGER E (US) 1999-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050008603-A1 Methods of making and using surfactant polymers MSR1, CD14, PLOD3 PRKCA 2602/4885NAAA 1899/4885DGKA 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.