SCHEMBL180331

SCHEMBL180331

N=C(N)Nc1ccc(CC(N)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.57
PTGS1 P23219 3/20 0.56
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
XIAP P98170 1/20 0.56
ITGB3 P05106 2/20 0.53
ITGA2B P08514 2/20 0.53
ITGAV P06756 1/20 0.53
TPH1 P17752 2/20 0.53
HIF1A Q16665 4/20 0.50
CYP3A4 P08684 3/20 0.50
ALOX15 P16050 3/20 0.50
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ABCB11 O95342 1/20 0.50
CHRM2 P08172 1/20 0.50
ADRA2A P08913 1/20 0.50
CHRM1 P11229 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289162 1.00 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL180332 1.00 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL26747607 0.87 ITGB3 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL1932906 0.87 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL169645 0.87 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL169646 0.87 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL7381598 0.85 ITGB3 (0.67) SLC7A5ITGB3ITGA2BITGAVALDH1A1
SCHEMBL7453923 0.85 ITGB3 (0.67) SLC7A5ITGB3ITGA2BITGAVALDH1A1
SCHEMBL6378833 0.84 LTA4H (0.48) SLC1A3SLC1A2SLC1A1
SCHEMBL8423623 0.84 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626479-A1 COMPOSITIONS AND METHODS FOR PROTEIN INTERNALIZATION Lytica Therapeutics, Inc. (US) 2025-10-08 EP claimed
EP-4522221-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS Entrada Therapeutics, Inc. (US) 2025-03-19 EP claimed
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES AIMMAX THERAPEUTICS, INC. 2024-10-31 US claimed
EP-4396196-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES Aimmax Therapeutics, Inc. (US) 2024-07-10 EP claimed
WO-2024119049-A1 COMPOSITIONS AND METHODS FOR PROTEIN INTERNALIZATION LYTICA THERAPEUTICS, INC. (US) 2024-06-06 WO claimed
EP-4359006-A1 ANTISENSE COMPOUNDS AND METHODS FOR TARGETING CUG REPEATS Entrada Therapeutics, Inc. (US) 2024-05-01 EP claimed
CN-117957022-A Antisense compounds and methods for targeting CUG repeats 安卓达治疗股份有限公司 2024-04-30 CN claimed
CN-117915957-A Compositions and methods for modulating mRNA splicing 恩特拉达治疗学股份有限公司 2024-04-19 CN claimed
CN-117897394-A Peptides with antimicrobial activity 美商安满药物开发公司 2024-04-16 CN claimed
EP-4337263-A1 COMPOSITIONS AND METHODS FOR MODULATING INTERFERON REGULATORY FACTOR-5 (IRF-5) ACTIVITY Entrada Therapeutics, Inc. (US) 2024-03-20 EP claimed
WO-2005042565-A2 CYCLIN GROOVE INHIBITORS CYCLACEL LIMITED (GB) 2005-05-12 WO claimed
US-6534546-B1 Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-03-18 US claimed
US-5990084-A A SERIES OF TRUNCATED ANALOGS OF HGHRH (HUMAN GROWTH HORMONE RELEASING HORMONE); ANALOG ACTIVATES THE GHRH RECEPTOR, BUT HAS IMPROVED METABOLIC STABILITY, DECREASED IMMUNOGENICITY AND LOWER COST OF PRODUCTION NOVO NORDISK A/S (DK) 1999-11-23 US claimed
EP-0910579-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1999-04-28 EP claimed
US-5874472-A Aminoacid derivatives as no synthase inhibitors GLAXO WELLCOME INC. (US) 1999-02-23 US claimed
EP-0705257-B1 AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS WELLCOME FOUND (GB) 1998-03-11 EP claimed
WO-1997040071-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-10-30 WO claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
EP-0705257-A1 AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1996-04-10 EP claimed
WO-1995000505-A1 AMINOACID DERIVATIVES AS NO SYNTHASE INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1995-01-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360177-A1 PEPTIDES WITH ANTIMICROBIAL ACTIVITIES VIP, FPR2, FPR1 SLC7A5 3654/4885PTGS1 1799/4885ALPI 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.