Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.53 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
| ▸ | TPH1 | P17752 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180331 | 1.00 | SLC7A5 (0.57) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL180332 | 1.00 | SLC7A5 (0.57) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL26747607 | 0.87 | ITGB3 (0.41) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL1932906 | 0.87 | SLC7A5 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL169645 | 0.87 | SLC7A5 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL169646 | 0.87 | SLC7A5 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7381598 | 0.85 | ITGB3 (0.67) | SLC7A5ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL7453923 | 0.85 | ITGB3 (0.67) | SLC7A5ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL6378833 | 0.84 | LTA4H (0.48) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8423623 | 0.84 | SLC7A5 (0.57) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695191-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2017-07-04 | — | — | US | claimed |
| EP-2462147-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2014-11-12 | — | — | EP | claimed |
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2012-08-09 | — | — | US | claimed |
| US-20050119190-A1 | Inhibitors of the blood-clotting factor xa, production thereof and use of the same | CURACYTE AG (DE) | 2005-06-02 | — | — | US | claimed |
| EP-1483285-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | Curacyte AG (DE) | 2004-12-08 | — | — | EP | claimed |
| WO-2003076457-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | claimed |
| US-4619914-A | PEPTIDES WHICH INHIBIT GONADOTROPIN SECRETION-CONTRACEPTIVES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-10-28 | — | — | US | claimed |
| US-20240010627-A1 | NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME | PEPTIDREAM INC. (JP) | 2024-01-11 | — | — | US | disclosed |
| EP-4276096-A1 | NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME | PeptiDream Inc. (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149610-A1 | NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME | ペプチドリーム株式会社 | 2022-07-14 | — | — | WO | disclosed |
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | disclosed |
| EP-3981784-A1 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-13 | — | — | EP | disclosed |
| US-10273267-B2 | Beta-hairpin peptidomimetics as selective elastase inhibitors | POLYPHOR AG (CH) | 2019-04-30 | — | — | US | disclosed |
| WO-1991012013-A1 | CYCLIC GnRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1991-08-22 | — | — | WO | disclosed |
| US-4661472-A | PREVENT OVULATION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1987-04-28 | — | — | US | disclosed |
| US-4652550-A | INHIBITING RELEASE OF GONADOTROPINS; PEPTIDES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0201260-A2 | GnRH antagonists | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4619914-A | PEPTIDES WHICH INHIBIT GONADOTROPIN SECRETION-CONTRACEPTIVES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0162575-A2 | GnRH Antagonists VII | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1985-11-27 | — | — | EP | disclosed |
| EP-0122712-A2 | GnRH antagonists | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1984-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202821-A1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | HTR2B, MC1R, HTR1A | SLC7A5 1600/4885PTGS1 109/4885ALPI 2014/4885 |
| US-20050119190-A1 | Inhibitors of the blood-clotting factor xa, production thereof and use of the same | SERPINC1, TFPI, F11 | SLC7A5 4712/4885PTGS1 1407/4885ALPI 2075/4885 |
| US-10273267-B2 | Beta-hairpin peptidomimetics as selective elastase inhibitors | SERPINB1, ELANE, XPNPEP1 | SLC7A5 1527/4885PTGS1 2416/4885ALPI 4162/4885 |
| US-20240010627-A1 | NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME | GMPS, MAPT, UROD | SLC7A5 89/4885PTGS1 1565/4885ALPI 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.