Sulfuric Acid

Sulfuric Acid

SCHEMBL18045136

C=CC(O)C1=NCCN1.O=S(=O)(O)O

nearest known ligand 0.35

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRA2B known ✓ P18089 13/20 0.35
ADRA2C known ✓ P18825 13/20 0.35
ADRA2A known ✓ P08913 12/20 0.35
MAOA known ✓ P21397 4/20 0.31
MAOB known ✓ P27338 4/20 0.31
RAD52 P43351 1/20 0.35
HTR1A P08908 2/20 0.33
KCNH2 Q12809 1/20 0.33
NISCH Q9Y2I1 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3264669 0.91
SCHEMBL11668041 0.80 NOS3 (0.38) ADRA2BADRA2CADRA2ANISCH
Sulfuric Acid SCHEMBL4063746 0.74 ADRA2A (0.43) RAD52ADRA2BADRA2CADRA2AHTR1A
Sulfuric Acid SCHEMBL588321 0.74 RAD52 (0.38) RAD52ADRA2AMAOAMAOBNISCH
Sulfuric Acid SCHEMBL27830459 0.73 ADRA2A (0.42) RAD52ADRA2BADRA2CADRA2AHTR1A
Sulfuric Acid SCHEMBL5982067 0.73 ADRA2A (0.42) RAD52ADRA2BADRA2CADRA2AHTR1A
Sulfuric Acid SCHEMBL27694869 0.73 ADRA2A (0.42) RAD52ADRA2BADRA2CADRA2AHTR1A
SCHEMBL1992259 0.71 ADRA2B (0.36) ADRA2BADRA2CADRA2AHTR1AKCNH2
SCHEMBL27826439 0.70 ADRA2B (0.36) ADRA2BADRA2CADRA2AHTR1AKCNH2
SCHEMBL4298623 0.70 NISCH (0.41) ADRA2BADRA2CADRA2AHTR1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10953640-B2 Thermoplastic resin sheets and formed articles NISSIN FOODS HOLDINGS CO., LTD. (JP) 2021-03-23 US disclosed
CN-206896206-U Eating utensil and instant food packaged in container 日清食品控股株式会社 2018-01-19 CN disclosed
US-20160263875-A1 THERMOPLASTIC RESIN SHEETS AND FORMED ARTICLES NISSIN FOODS HOLDINGS CO., LTD. (JP) 2016-09-15 US disclosed