Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805334 | 0.79 | L3MBTL1 (0.57) | CES1L3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL13712393 | 0.78 | CES1 (1.00) | CES1L3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL15763745 | 0.73 | PNMT (0.35) | — | |
| SCHEMBL29408351 | 0.73 | CES1 (0.90) | CES1L3MBTL1TDP1ALDH1A1MAPT | |
| SCHEMBL44496 | 0.73 | CES1 (0.90) | CES1L3MBTL1TDP1ALDH1A1MAPT | |
| SCHEMBL29437756 | 0.73 | CES1 (0.90) | CES1L3MBTL1TDP1ALDH1A1MAPT | |
| SCHEMBL18045592 | 0.73 | PTPRC (0.47) | CES1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL8254678 | 0.72 | PKM (0.30) | PKM | |
| SCHEMBL17865606 | 0.72 | PBRM1 (0.31) | — | |
| SCHEMBL4165344 | 0.70 | CES1 (0.61) | CES1L3MBTL1TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319840-B1 | AMINOPROPYLIDENE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2015-12-16 | — | — | EP | disclosed |
| US-8653285-B2 | Aminopropylidene derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| US-20110124856-A1 | AMINOPROPYLIDENE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-2319840-A1 | AMINOPROPYLIDENE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2011-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124856-A1 | AMINOPROPYLIDENE DERIVATIVE | HRH2, HRH3, HRH4 | CES1 2989/4885L3MBTL1 564/4885TDP1 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.