Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | GSK3B | P49841 | 9/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18049419 | 0.86 | PTGS2 (0.60) | PTGS2GSK3B | |
| SCHEMBL3815134 | 0.78 | PTGS2 (0.65) | PTGS2GSK3BPOLB | |
| SCHEMBL5762155 | 0.78 | ACHE (0.48) | PTGS2GSK3BDAPK3NTRK1PIM1 | |
| SCHEMBL114611 | 0.78 | PTGS2 (0.67) | PTGS2GSK3B | |
| SCHEMBL3822129 | 0.77 | PTGS2 (0.57) | PTGS2GSK3B | |
| SCHEMBL18049424 | 0.77 | PTGS2 (0.57) | PTGS2GSK3BCLK4 | |
| SCHEMBL9474080 | 0.75 | PTGS2 (0.64) | PTGS2GSK3B | |
| SCHEMBL3816794 | 0.74 | GSK3B (0.67) | PTGS2GSK3B | |
| SCHEMBL9237602 | 0.74 | PTGS2 (0.54) | PTGS2GSK3B | |
| SCHEMBL934146 | 0.74 | GSK3B (0.65) | PTGS2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144352-A2 | THERAPEUTIC COMPOSITIONS INCLUDING ACRYLAMIDO COMPOUNDS OR PHENYL-SUBSTITUTED MALEIMIDE COMPOUNDS, VARIANTS THEREOF AND METHODS OF USING THE SAME | STEALTH PEPTIDES INTERNATIONAL, INC. (MC) | 2016-09-15 | — | — | WO | disclosed |