SCHEMBL1804979

SCHEMBL1804979

O=S(=O)(Oc1ccc(N(c2cccc3c2sc2ccccc23)c2cccc3c2sc2ccccc23)cc1)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ PTPN7 P35236 1/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ PTPN12 Q05209 1/20 0.33
▸ PTPN22 Q9Y2R2 1/20 0.33
▸ STS P08842 1/20 0.31
▸ TRPM8 Q7Z2W7 1/20 0.31
▸ PARP14 Q460N5 1/20 0.30
▸ HTR1A P08908 1/20 0.30
▸ HTR1D P28221 1/20 0.30
▸ HTR1B P28222 1/20 0.30
▸ GPR3 P46089 1/20 0.30
▸ CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16596209 0.85 ALOX5 (0.43) CA1CA2PTPN7DUSP3PTPN12
SCHEMBL23871157 0.82 STS (0.32) PTPN7DUSP3PTPN12PTPN22STS
SCHEMBL18164797 0.80 — —
SCHEMBL18164693 0.79 ALOX5 (0.40) PARP14
SCHEMBL17030508 0.79 ALOX5 (0.48) CA1CA2PTPN7DUSP3PTPN12
SCHEMBL15964349 0.79 GPR3 (0.45) PARP14GPR3
SCHEMBL1804299 0.78 MAPT (0.45) —
SCHEMBL14295423 0.77 GPR3 (0.43) PARP14GPR3
SCHEMBL3718035 0.77 ALOX5 (0.38) CA1CA2PARP14HTR1DGPR3
SCHEMBL15964350 0.76 ALOX5 (0.42) PARP14GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 — — US disclosed
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 — — US disclosed
EP-2628778-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2016-03-16 — — EP disclosed
EP-2628778-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2016-03-16 — — EP disclosed
US-8652653-B2 Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 — — US disclosed
US-8652653-B2 Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 — — US disclosed
US-8652653-B2 Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 — — US disclosed
EP-2628778-A1 Hole transport materials having a sulfur-containing group Universal Display Corporation (US) 2013-08-21 — — EP disclosed
EP-2628778-A1 Hole transport materials having a sulfur-containing group Universal Display Corporation (US) 2013-08-21 — — EP disclosed
EP-2321376-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2013-06-19 — — EP disclosed
EP-2321376-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2013-06-19 — — EP disclosed
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2011-07-07 — — US disclosed
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2011-07-07 — — US disclosed
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2011-07-07 — — US disclosed
EP-2321376-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP Universal Display Corporation (US) 2011-05-18 — — EP disclosed
WO-2010002848-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2010-01-07 — — WO disclosed
WO-2010002848-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2010-01-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 CA1 2950/4885CA2 3744/4885PTPN7 4487/4885
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP TST, SLC43A1, SLC6A4 CA1 4828/4885CA2 4576/4885PTPN7 4146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback