Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050887 | 0.88 | PKM (0.53) | PKMGAATSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL20366124 | 0.84 | PKM (0.58) | PKMGAATSHRAPOBEC3AAPOBEC3G | |
| Methylamine SCHEMBL6091448 | 0.82 | PKM (0.57) | PKMGAATSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL21314978 | 0.81 | PKM (0.44) | PKMGAATSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL28314802 | 0.81 | CYP2C19 (0.43) | PKMGAATSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL18050889 | 0.77 | MEN1 (0.42) | APOBEC3AAPOBEC3GCYP2C19ADORA2APDE4A | |
| SCHEMBL11491981 | 0.76 | PKM (0.75) | PKMGAATSHR | |
| SCHEMBL27896031 | 0.76 | KDM4E (0.43) | PKMGAATSHRCYP2C19L3MBTL1 | |
| SCHEMBL67836 | 0.75 | APOBEC3A (0.50) | PKMGAATSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL20591073 | 0.75 | ALDH1A1 (0.40) | GAAAPOBEC3AAPOBEC3GADORA2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230398226-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | CIDARA THERAPEUTICS, INC. | 2023-12-14 | — | — | US | disclosed |
| US-11833213-B2 | Compositions and methods for the treatment of viral infections | CIDARA THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230287365-A1 | COMPOSITIONS AND METHODS FOR DECREASING INFLAMMATION | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2023-09-14 | — | — | US | disclosed |
| US-20230190950-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |
| EP-4188993-A1 | A POLYESTER MOLDING COMPRISING A METAL-ORGANIC FRAMEWORK HAVING A LOW OUTGASSING OF VOLATILE ORGANIC COMPOUNDS | BASF SE (DE) | 2023-06-07 | — | — | EP | disclosed |
| CN-104672145-B | Glycalpyramide derivative and application thereof in preparing anticoccidial drug | 广州英赛特生物技术有限公司 | 2017-04-12 | — | — | CN | disclosed |
| WO-2016141736-A1 | GLYCALPYRAMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF ANTICOCCIDIAL DRUG | 广州英赛特生物技术有限公司 | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230398226-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | FCGR3B, ALB, FCGR1A | PKM 4394/4885GAA 159/4885TSHR 2184/4885 |
| US-20230190950-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | FCGR3B, FCGR1A, FCGR2A | PKM 4802/4885GAA 2534/4885TSHR 2359/4885 |
| US-11833213-B2 | Compositions and methods for the treatment of viral infections | FCGR3B, ALB, FCGR1A | PKM 4394/4885GAA 159/4885TSHR 2184/4885 |
| US-20230287365-A1 | COMPOSITIONS AND METHODS FOR DECREASING INFLAMMATION | ENTPD1, ENTPD2, ENTPD5 | PKM 2537/4885GAA 292/4885TSHR 3422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.