Methylamine

Methylamine

SCHEMBL6091448

CCn1cnc(C(=O)O)c1C(=O)O.CCn1cnc(C(=O)O)c1C(=O)O.CN.CN

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.57
GAA P10253 1/20 0.57
TSHR P16473 1/20 0.57
NPC1 O15118 1/20 0.43
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
ADORA2A P29274 2/20 0.34
ADORA1 P30542 1/20 0.34
PI4KA P42356 1/20 0.34
PI4K2B Q8TCG2 1/20 0.34
PI4K2A Q9BTU6 1/20 0.34
PI4KB Q9UBF8 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CDK1 P06493 2/20 0.33
CCNB1 P14635 2/20 0.33
CCNE1 P24864 2/20 0.33
CDK2 P24941 2/20 0.33
MEN1 O00255 1/20 0.33
PABPC1 P11940 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18050872 0.82 PKM (0.57) PKMGAATSHRNPC1APOBEC3A
SCHEMBL20552051 0.80 PKM (0.42) PKMGAATSHRNPC1APOBEC3A
SCHEMBL7987138 0.78 PKM (0.44) PKMGAATSHRNPC1ADORA2A
SCHEMBL20366124 0.76 PKM (0.58) PKMGAATSHRNPC1APOBEC3A
SCHEMBL1951450 0.76 ALDH1A1 (0.42) PKMGAATSHRNPC1APOBEC3A
Methylamine SCHEMBL5149607 0.76 APOBEC3A (0.47) PKMGAATSHRNPC1APOBEC3A
SCHEMBL12724350 0.74 ALDH1A1 (0.44) PKMGAATSHRNPC1APOBEC3A
SCHEMBL11484479 0.72 TSHR (0.75) PKMGAATSHRNPC1MEN1
SCHEMBL4802244 0.71 PTGS2 (0.53) PKMGAATSHRNPC1MEN1
SCHEMBL15825866 0.71 ALDH1A1 (0.41) PKMGAATSHRNPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060135587-A1 Method and compounds for promoting healing and reducing inflammation BIODIEM, LTD. (AU) 2006-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135587-A1 Method and compounds for promoting healing and reducing inflammation IL1B, MIF, ALKBH5 PKM 1865/4885GAA 4723/4885TSHR 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.