Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.62 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17705682 | 0.87 | CARM1 (0.63) | SIGMAR1CARM1PRMT6PRMT8APP | |
| SCHEMBL29733117 | 0.83 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8ACHE | |
| SCHEMBL7225346 | 0.83 | SIGMAR1 (0.85) | SIGMAR1CARM1PRMT6PRMT8ACHE | |
| SCHEMBL15966154 | 0.83 | SIGMAR1 (0.67) | SIGMAR1CARM1PRMT6PRMT8APP | |
| SCHEMBL15966146 | 0.83 | SIGMAR1 (0.67) | SIGMAR1CARM1PRMT6PRMT8APP | |
| SCHEMBL15966156 | 0.83 | SIGMAR1 (0.67) | SIGMAR1CARM1PRMT6PRMT8APP | |
| SCHEMBL1088446 | 0.81 | SIGMAR1 (0.74) | SIGMAR1CARM1PRMT6PRMT8ACHE | |
| SCHEMBL4604745 | 0.80 | CARM1 (0.75) | SIGMAR1CARM1PRMT6PRMT8ACHE | |
| Hydrochloric Acid SCHEMBL1087168 | 0.79 | SIGMAR1 (0.71) | SIGMAR1CARM1PRMT6PRMT8ACHE | |
| SCHEMBL15783060 | 0.79 | SIGMAR1 (0.57) | SIGMAR1CARM1PRMT6PRMT8APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439968-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |