Sugi Predict

Sugi Predict / Compounds / SCHEMBL1807289

SCHEMBL1807289

SCHEMBL1807289

NCCc1ccc(-c2ccc(Cl)c(Cl)c2)o1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.47
▸ PNMT P11086 1/20 0.47
▸ TAAR1 Q96RJ0 1/20 0.47
▸ HRH1 P35367 1/20 0.46
▸ HPGD P15428 5/20 0.45
▸ MAPT P10636 4/20 0.45
▸ MEN1 O00255 4/20 0.45
▸ KMT2A Q03164 4/20 0.45
▸ HTT P42858 2/20 0.45
▸ AHR P35869 2/20 0.43
▸ PKM P14618 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ GFER P55789 1/20 0.43
▸ FTO Q9C0B1 1/20 0.42
▸ SIRT2 Q8IXJ6 1/20 0.42
▸ GAA P10253 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1806909 0.98 ALDH1A1 (0.46) ALDH1A1NPSR1PNMTTAAR1HRH1
SCHEMBL11832976 0.86 CYP3A4 (0.56) ALDH1A1NPSR1HPGDMAPTMEN1
SCHEMBL12075896 0.79 AHR (0.46) ALDH1A1NPSR1HPGDMAPTMEN1
SCHEMBL1812018 0.76 ALDH1A1 (0.45) ALDH1A1NPSR1HPGDMAPTMEN1
SCHEMBL1810429 0.76 PNMT (0.51) ALDH1A1NPSR1PNMTHPGDMAPT
SCHEMBL12075895 0.76 ALDH1A1 (0.45) ALDH1A1NPSR1HPGDMAPTMEN1
Hydrochloric Acid SCHEMBL1810953 0.74 PNMT (0.50) ALDH1A1NPSR1PNMTHPGDMAPT
Hydrochloric Acid SCHEMBL15841782 0.74 ALDH1A1 (0.44) ALDH1A1NPSR1HPGDMAPTMEN1
SCHEMBL4653824 0.74 CYP2C19 (0.71) ALDH1A1NPSR1TAAR1HRH1HPGD
Hydrochloric Acid SCHEMBL9480134 0.71 FTO (0.47) ALDH1A1HPGDMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 — — EP disclosed
EP-3885340-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2021-09-29 — — EP disclosed
US-11046713-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2021-06-29 — — US disclosed
EP-3369732-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2021-05-26 — — EP disclosed
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2020-09-24 — — US disclosed
US-10711013-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2020-07-14 — — US disclosed
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2019-04-04 — — US disclosed
US-10118933-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2018-11-06 — — US disclosed
EP-3369732-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2018-09-05 — — EP disclosed
US-20170260206-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2017-09-14 — — US disclosed
US-9657003-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2017-05-23 — — US disclosed
EP-3056485-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS Orion Corporation (FI) 2016-08-17 — — EP disclosed
US-20150203479-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION 2015-07-23 — — US disclosed
US-8975254-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2015-03-10 — — US disclosed
EP-2493858-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2014-07-02 — — EP disclosed
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-09-06 — — US disclosed
EP-2493858-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS Orion Corporation (FI) 2012-09-05 — — EP disclosed
WO-2011051540-A9 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-06-21 — — WO disclosed
WO-2011051540-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2011-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260206-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-10118933-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-10711013-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-11046713-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-20150203479-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG ALDH1A1 570/4885NPSR1 97/4885PNMT 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.