SCHEMBL18079537

SCHEMBL18079537

C=C(C)C(=C)OCCNS(=O)(=O)C(F)(F)C(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16866880 0.87 THRB (0.38) ALDH1A1TP53SMN1; SMN2
SCHEMBL10053107 0.84 EPHX1 (0.42)
SCHEMBL217339 0.71 THRB (0.42) ALDH1A1SMN1; SMN2
SCHEMBL2632780 0.67 CA1 (0.40) ALDH1A1
SCHEMBL9946240 0.66 EPHX1 (0.46) ALDH1A1SMN1; SMN2
SCHEMBL10212543 0.66 CA1 (0.46) ALDH1A1
SCHEMBL15298034 0.65 ACHE (0.31)
SCHEMBL13263775 0.65 EPHX1 (0.38)
SCHEMBL14769572 0.65 THRB (0.42) ALDH1A1
SCHEMBL15681507 0.64 EPHX1 (0.43) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9448486-B2 Photoresist pattern trimming compositions and methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-09-20 US disclosed