Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15756398 | 0.84 | GPR84 (0.56) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL1410027 | 0.84 | CACNA2D1 (0.74) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL967149 | 0.84 | ADRA1A (0.48) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL4412290 | 0.84 | CACNA2D1 (0.74) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL1335604 | 0.84 | ADRA1A (0.48) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL5695204 | 0.83 | CACNA2D1 (0.47) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL27800850 | 0.83 | CACNA2D1 (0.61) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL27821717 | 0.83 | CACNA2D1 (0.61) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL27800888 | 0.83 | CACNA2D1 (0.61) | CACNA2D1ADRA1ACACNB3CACNA1CPGR | |
| SCHEMBL12878966 | 0.82 | CACNA2D1 (0.65) | CACNA2D1ADRA1ACACNB3CACNA1CPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160266153-A1 | IMMUNOASSAY FOR PREGABALIN | RANDOX LABORATORIES LIMITED (GB) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160266153-A1 | IMMUNOASSAY FOR PREGABALIN | GABRG1, GABRG3, GABRG2 | CACNA2D1 84/4885ADRA1A 1286/4885CACNB3 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.