Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799557 | 0.79 | LMNA (0.44) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL1031488 | 0.79 | LMNA (0.71) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL21874545 | 0.75 | MAPT (0.51) | LMNAALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31490853 | 0.75 | MAPT (0.51) | LMNAALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL15619431 | 0.73 | BCL2L1 (0.53) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL17149269 | 0.73 | LMNA (0.50) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL10949281 | 0.72 | MAPK1 (0.45) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL4656286 | 0.72 | CES2 (0.61) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL15910659 | 0.72 | L3MBTL1 (0.58) | LMNAMAPK1ALDH1A1MAPTHPGD | |
| SCHEMBL9756981 | 0.72 | MAPK1 (0.53) | LMNAMAPK1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |