Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173402 | 0.83 | CYP17A1 (0.39) | CYP17A1CYP1A2FLT3GSK3BMAPT | |
| SCHEMBL17173554 | 0.83 | CYP17A1 (0.38) | CYP17A1CYP1A2FLT3GSK3BMAPT | |
| SCHEMBL12514329 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3791621 | 0.79 | MEN1 (0.56) | CYP17A1CYP1A2 | |
| SCHEMBL26350115 | 0.78 | CYP17A1 (0.39) | CYP17A1CYP1A2GRM4MAPTCA12 | |
| SCHEMBL12153468 | 0.75 | SIGMAR1 (0.48) | MAPTBRD4BRD2BRD3TDP1 | |
| SCHEMBL30261935 | 0.75 | SIGMAR1 (0.48) | MAPTBRD4BRD2BRD3TDP1 | |
| SCHEMBL26103577 | 0.75 | SMN1; SMN2 (0.48) | CYP17A1CYP1A2MAPTALDH1A1LMNA | |
| SCHEMBL17754707 | 0.75 | FLT3 (0.39) | CYP17A1CYP1A2FLT3GSK3BMAPT | |
| SCHEMBL26350148 | 0.74 | CYP17A1 (0.39) | CYP17A1CYP1A2GRM4MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160276603-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2016-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160276603-A1 | Organic Electroluminescent Materials and Devices | EML4, BICRA, TBCB | CYP17A1 4698/4885CYP1A2 1813/4885GRM4 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.