Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193973 | 0.83 | ROCK1 (0.50) | SMN1; SMN2ROCK1ALDH1A1MEN1KMT2A | |
| SCHEMBL798870 | 0.81 | CYP11B2 (0.47) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL25026229 | 0.81 | ALDH1A1 (0.55) | SMN1; SMN2ROCK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9191760 | 0.79 | ROCK1 (0.50) | SMN1; SMN2ROCK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9767604 | 0.78 | ALOX15 (0.51) | SMN1; SMN2ROCK1ALDH1A1MEN1KMT2A | |
| SCHEMBL9196015 | 0.76 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9194662 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2ROCK1ALDH1A1MEN1KMT2A | |
| SCHEMBL18088239 | 0.75 | CYP17A1 (0.48) | ALDH1A1LMNAMAPK1MAPTCYP17A1 | |
| SCHEMBL807995 | 0.75 | CYP11B2 (0.42) | SRD5A1MAPT | |
| SCHEMBL807907 | 0.75 | CYP11B2 (0.43) | MAPTHTR2CCYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |