Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18089735 | 0.78 | ALDH1A1 (0.40) | TP53ALOX15HSD17B10PKM | |
| SCHEMBL15861604 | 0.76 | TP53 (0.36) | TP53ALOX15HSD17B10 | |
| SCHEMBL15861605 | 0.76 | TP53 (0.36) | TP53ALOX15HSD17B10 | |
| SCHEMBL18089666 | 0.72 | SMN1; SMN2 (0.40) | HSD17B10PKM | |
| SCHEMBL18089740 | 0.72 | ALDH1A1 (0.34) | HSD17B10 | |
| SCHEMBL18089423 | 0.72 | ALDH1A1 (0.34) | HSD17B10 | |
| SCHEMBL18089741 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL19886700 | 0.69 | ALDH1A1 (0.37) | TP53ALOX15HSD17B10PKM | |
| SCHEMBL18089736 | 0.67 | CYP2C9 (0.33) | ALOX15HSD17B10PKM | |
| SCHEMBL21497101 | 0.66 | CYP2C9 (0.34) | ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618918-B2 | Substituted boronic acids as antimicrobials | QPEX BIOPHARMA, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | REMPEX PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | REMPEX PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20180051041-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | THE MEDICINES COMPANY (SAN DIEGO), LLC | 2018-02-22 | — | — | US | disclosed |
| US-20180051041-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | THE MEDICINES COMPANY (SAN DIEGO), LLC | 2018-02-22 | — | — | US | disclosed |
| WO-2016149393-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2016-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051041-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | BCL6B, BTD, BCL6 | TP53 855/4885ALOX15 2506/4885HSD17B10 3364/4885 |
| US-10618918-B2 | Substituted boronic acids as antimicrobials | ABCB11, BRS3, SLC10A2 | TP53 4109/4885ALOX15 2229/4885HSD17B10 3182/4885 |
| US-20190211037-A1 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES IN ANTIMICROBIAL TREATMENT | BTD, BCL6B, BPGM | TP53 1696/4885ALOX15 3599/4885HSD17B10 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.