Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809009 | 1.00 | NPC1 (0.40) | NPC1RAB9APKMMAPTATM | |
| SCHEMBL1806743 | 0.86 | EPHX2 (0.39) | PKMMAPTEPHX2ADCY8ADCY1 | |
| SCHEMBL1807398 | 0.74 | AR (0.50) | — | |
| SCHEMBL1806730 | 0.74 | DDR1 (0.41) | NPC1RAB9AMAPTEPHX2ADCY8 | |
| SCHEMBL15492067 | 0.70 | HPGD (0.49) | NPC1RAB9APKMALDH1A1POLB | |
| SCHEMBL28553348 | 0.67 | LMNA (0.58) | MAPTHDAC3HTT | |
| SCHEMBL5307396 | 0.67 | ALDH1A1 (0.40) | NPC1RAB9APKMMAPTATM | |
| SCHEMBL30292169 | 0.67 | ALDH1A1 (0.40) | NPC1RAB9APKMMAPTATM | |
| SCHEMBL4880854 | 0.67 | CES2 (0.46) | PKMMAPTEPHX2ALDH1A1KDM4E | |
| SCHEMBL5307395 | 0.67 | ALDH1A1 (0.40) | NPC1RAB9APKMMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563779-A1 | INSECTICIDAL ARYLPYRROLINE COMPOUNDS | Bayer CropScience AG (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-8158560-B2 | Insecticidal arylpyrroline compounds | BAYER CROPSCIENCE AG (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| WO-2011054871-A1 | INSECTICIDAL ARYLPYRROLINE COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118319-A1 | Insecticidal Arylpyrroline Compounds | DDT, LAP3, CYP4X1 | NPC1 4027/4885RAB9A 797/4885PKM 2397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.