Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 9/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18090576 | 0.86 | POLB (0.46) | LMNAEDNRA | |
| SCHEMBL22261624 | 0.75 | LMNA (0.44) | LMNANPSR1FABP4FABP3FABP2 | |
| SCHEMBL28034923 | 0.74 | HSD11B1 (0.56) | LMNAKMT2AKDM4E | |
| SCHEMBL17908025 | 0.72 | LMNA (1.00) | LMNANPSR1FABP4FABP3FABP2 | |
| SCHEMBL2531253 | 0.71 | LMNA (0.68) | LMNANPSR1FABP4FABP3FABP2 | |
| SCHEMBL3821615 | 0.71 | LMNA (0.58) | LMNANPSR1FABP4FABP3FABP2 | |
| SCHEMBL6361732 | 0.71 | NPSR1 (0.51) | NPSR1MEN1KMT2A | |
| SCHEMBL1864283 | 0.70 | ALDH1A1 (0.51) | LMNAKDM4E | |
| SCHEMBL11472500 | 0.69 | LMNA (0.65) | LMNANPSR1FABP4FABP3FABP2 | |
| SCHEMBL1858049 | 0.69 | ALDH1A1 (0.39) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9440954-B2 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-09-13 | — | — | US | disclosed |
| US-9440954-B2 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-09-13 | — | — | US | disclosed |
| CN-104334542-A | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2015-02-04 | — | — | CN | disclosed |