Sugi Predict

Sugi Predict / Compounds / SCHEMBL1809100

SCHEMBL1809100

SCHEMBL1809100

CCOC(=O)C(=O)NCC(=O)OC

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TET2 Q6N021 1/20 0.69
▸ EGLN1 Q9GZT9 2/20 0.68
▸ RECQL P46063 1/20 0.45
▸ GAA P10253 5/20 0.44
▸ MGAM O43451 1/20 0.44
▸ SI P14410 1/20 0.44
▸ MGAM2 Q2M2H8 1/20 0.44
▸ ALDH1A1 P00352 4/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ GPR35 Q9HC97 2/20 0.39
▸ TSHR P16473 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5854855 0.89 EGLN1 (0.70) TET2EGLN1GAAMGAMSI
SCHEMBL18039340 0.83 TET2 (0.69) TET2EGLN1GAAMGAMSI
SCHEMBL21679321 0.82 EGLN1 (0.61) TET2EGLN1GAAMGAMSI
SCHEMBL3700532 0.82 TET2 (1.00) TET2EGLN1RECQLGAAMGAM
SCHEMBL1979843 0.81 EGLN1 (0.70) TET2EGLN1GAAMGAMSI
SCHEMBL12521171 0.81 EGLN1 (1.00) TET2EGLN1GAAMGAMSI
SCHEMBL1980217 0.80 EGLN1 (0.63) TET2EGLN1GAAMGAMSI
SCHEMBL1337998 0.80 EGLN1 (0.58) TET2EGLN1GAAALDH1A1TDP1
SCHEMBL18834082 0.79 EGLN1 (0.68) TET2EGLN1GAAMGAMSI
SCHEMBL11184401 0.78 ALDH1A1 (0.56) TET2EGLN1RECQLGAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174907-B Environment-friendly preparation method of substituted oxazole compound 新发药业有限公司 2022-08-12 — — CN claimed
US-20220112168-A1 Environment-friendly preparation method of a substituted oxazole compound XIN FA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US claimed
CN-112174907-A Environment-friendly preparation method of substituted oxazole compound 新发药业有限公司 2021-01-05 — — CN claimed
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 — — EP disclosed
US-20220112168-A1 Environment-friendly preparation method of a substituted oxazole compound XIN FA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
EP-3885340-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2021-09-29 — — EP disclosed
US-11046713-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2021-06-29 — — US disclosed
EP-3369732-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2021-05-26 — — EP disclosed
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2020-09-24 — — US disclosed
US-10711013-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2020-07-14 — — US disclosed
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2019-04-04 — — US disclosed
WO-2016135163-A1 ALKYNYL ALCOHOLS AND METHODS OF USE F. HOFFMANN-LA ROCHE AG (CH) 2016-09-01 — — WO disclosed
EP-3056485-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS Orion Corporation (FI) 2016-08-17 — — EP disclosed
US-20150203479-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION 2015-07-23 — — US disclosed
US-8975254-B2 Androgen receptor modulating compounds ORION CORPORATION (FI) 2015-03-10 — — US disclosed
EP-2493858-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2014-07-02 — — EP disclosed
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-09-06 — — US disclosed
EP-2493858-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS Orion Corporation (FI) 2012-09-05 — — EP disclosed
WO-2011051540-A9 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2012-06-21 — — WO disclosed
WO-2011051540-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2011-05-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112168-A1 Environment-friendly preparation method of a substituted oxazole compound OGFOD1, DDO, GLUL TET2 1903/4885EGLN1 696/4885RECQL 4505/4885
US-10711013-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG TET2 3942/4885EGLN1 3288/4885RECQL 3067/4885
US-20200299307-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG TET2 3942/4885EGLN1 3288/4885RECQL 3067/4885
US-20190100536-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG TET2 3942/4885EGLN1 3288/4885RECQL 3067/4885
US-11046713-B2 Androgen receptor modulating compounds AR, NR5A1, SHBG TET2 3942/4885EGLN1 3288/4885RECQL 3067/4885
US-20150203479-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG TET2 3942/4885EGLN1 3288/4885RECQL 3067/4885
US-20120225867-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS AR, NR5A1, SHBG TET2 3942/4885EGLN1 3288/4885RECQL 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.